HPVomics

Efficient putative HR-HPVs E1^E4 protein epitopes (MHC-I Binders)

S.No.	HPV type	Target region	Peptide seuences	Start	End	Length	Allele	Percentile rank	ann_ic50	smm_ic50
1	HPV16	E1^E4	LSCCTETQW	59	67	9	HLA-B*58:01	0.2	4.43	10.6
2	HPV16	E1^E4	STWPTTPPR	18	26	9	HLA-A*31:01	0.25	8.81	19.34
3	HPV16	E1^E4	TTPPRPIPK	22	30	9	HLA-A*11:01	0.35	21.99	33.75
4	HPV16	E1^E4	SSLHLTAHTK	72	81	10	HLA-A*11:01	0.35	29.94	27.53
5	HPV18	E1^E4	RPTARRRLL	38	46	9	HLA-B*07:02	0.1	4.92	4.33
6	HPV18	E1^E4	YPLLSLLNSY	12	21	10	HLA-B*35:01	0.2	20.76	33.72
7	HPV18	E1^E4	VPVTTRYPL	6	14	9	HLA-B*07:02	0.3	7.74	26.36
8	HPV18	E1^E4	RLLHDLDTV	44	52	9	HLA-A*02:06	0.4	5.91	19.48
9	HPV18	E1^E4	RLLHDLDTV	44	52	9	HLA-A*02:01	0.6	16.88	32.22
10	HPV18	E1^E4	RLLHDLDTV	44	52	9	HLA-A*02:03	0.95	15.66	37.67
11	HPV26	E1^E4	WTIQTTTYTV	75	84	10	HLA-A*68:02	0.15	7.62	15.75
12	HPV26	E1^E4	LPHSPDSQW	67	75	9	HLA-B*53:01	0.2	13.75	12.24
13	HPV26	E1^E4	YTVQVEAITR	82	91	10	HLA-A*68:01	0.2	12	6.7
14	HPV26	E1^E4	APRKPRRHT	36	44	9	HLA-B*07:02	0.2	11.45	18.15
15	HPV26	E1^E4	SQWTIQTTTY	73	82	10	HLA-B*15:01	0.25	13.73	2.33
16	HPV26	E1^E4	EAITREGTR	87	95	9	HLA-A*68:01	0.3	17.28	18.47
17	HPV26	E1^E4	QTTTYTVQV	78	86	9	HLA-A*68:02	0.5	12.95	32.48
18	HPV31	E1^E4	YPLLGLLQSY	10	19	10	HLA-B*35:01	0.25	28.45	31.04
19	HPV31	E1^E4	TTPPHRIPK	23	31	9	HLA-A*11:01	0.3	18.21	20.57
20	HPV31	E1^E4	WTVSTVGLSV	72	81	10	HLA-A*68:02	0.5	37.24	27.31
21	HPV33	E1^E4	YPLLKLLTY	9	17	9	HLA-B*35:01	0.3	5.5	12.9
22	HPV33	E1^E4	MADPEATKY	1	9	9	HLA-B*35:01	0.5	16.52	26.22
23	HPV35	E1^E4	APQKPRRQI	35	43	9	HLA-B*07:02	0.2	9.89	21.82
24	HPV35	E1^E4	YPLLKLLHSY	10	19	10	HLA-B*35:01	0.25	38.76	36.97
25	HPV35	E1^E4	RQITNDFEGV	41	50	10	HLA-A*02:06	0.25	13.01	16.94
26	HPV35	E1^E4	AAQNYPLLK	6	14	9	HLA-A*11:01	0.35	13.95	29.33
27	HPV35	E1^E4	TTPPRPIPK	22	30	9	HLA-A*11:01	0.35	21.99	33.75
28	HPV35	E1^E4	AAAQNYPLLK	5	14	10	HLA-A*11:01	0.35	29.85	27.34
29	HPV35	E1^E4	STLHLTAQTK	73	82	10	HLA-A*11:01	0.35	25.94	27.09
30	HPV39	E1^E4	YPLLNLLPNY	12	21	10	HLA-B*35:01	0.15	14.25	26.42
31	HPV39	E1^E4	ILTTHSTVTV	66	75	10	HLA-A*02:03	0.5	24.8	15.75
32	HPV39	E1^E4	GTSVVVTLR	82	90	9	HLA-A*68:01	0.5	17.02	32.17
33	HPV39	E1^E4	WTILTTHSTV	64	73	10	HLA-A*68:02	0.55	25.21	35.02
34	HPV39	E1^E4	TQDGTSVVV	79	87	9	HLA-A*02:06	0.9	32.55	34.24
35	HPV45	E1^E4	NPTSRRRLL	38	46	9	HLA-B*07:02	0.2	23.88	25.11
36	HPV45	E1^E4	VPVTTRYPL	6	14	9	HLA-B*07:02	0.3	7.74	26.36
37	HPV45	E1^E4	RLLSDLDSV	44	52	9	HLA-A*02:06	0.35	5.83	17.36
38	HPV45	E1^E4	RLLSDLDSV	44	52	9	HLA-A*02:01	0.5	9.41	22.55
39	HPV45	E1^E4	RLLSDLDSV	44	52	9	HLA-A*02:03	0.65	9.81	24.32
40	HPV51	E1^E4	VPAATRYPL	5	13	9	HLA-B*07:02	0.1	4.73	7.76
41	HPV51	E1^E4	RPIPLPPAW	25	33	9	HLA-B*53:01	0.2	12.56	35.31
42	HPV51	E1^E4	EVPAATRYPL	4	13	10	HLA-A*68:02	0.35	7.11	27.44
43	HPV51	E1^E4	QTTKYTVEV	64	72	9	HLA-A*68:02	0.5	18.16	29.42
44	HPV51	E1^E4	WTIQTTKYTV	61	70	10	HLA-A*68:02	0.55	12.51	33.75
45	HPV51	E1^E4	GTKVQLRLR	79	87	9	HLA-A*31:01	0.6	34.76	37.97
46	HPV52	E1^E4	KTHTYNHHR	33	41	9	HLA-A*31:01	0.15	4.96	5.08
47	HPV52	E1^E4	YPLLKLLSTY	9	18	10	HLA-B*35:01	0.2	21.67	30.82
48	HPV52	E1^E4	STYAPKPPR	16	24	9	HLA-A*31:01	0.25	10.28	14.3
49	HPV52	E1^E4	KLLSTYAPK	13	21	9	HLA-A*30:01	0.5	10.98	29.44
50	HPV53	E1^E4	KLLTNTTPI	16	24	9	HLA-A*32:01	0.2	6.31	5.15
51	HPV53	E1^E4	VPLDPTYPL	6	14	9	HLA-B*07:02	0.3	13.78	32.43
52	HPV53	E1^E4	TTPENTSLV	83	91	9	HLA-A*68:02	0.3	7.29	17.93
53	HPV53	E1^E4	ENTSLVELR	86	94	9	HLA-A*68:01	0.35	19.29	18.6
54	HPV56	E1^E4	TTTLVIRLR	89	97	9	HLA-A*68:01	0.15	12.9	11
55	HPV56	E1^E4	TTTTTLVIR	87	95	9	HLA-A*68:01	0.2	12.06	14.34
56	HPV56	E1^E4	EVSTTTTTLV	84	93	10	HLA-A*68:02	0.35	22.16	17.51
57	HPV56	E1^E4	TTTTLVIRLR	88	97	10	HLA-A*68:01	0.45	15.4	25
58	HPV58	E1^E4	KLLTQRPPR	13	21	9	HLA-A*31:01	0.3	11.84	12.37
59	HPV58	E1^E4	EVIKYPLLK	5	13	9	HLA-A*68:01	0.35	15.24	22.41
60	HPV58	E1^E4	TVQLTVHTK	66	74	9	HLA-A*11:01	0.4	34.84	39.2
61	HPV58	E1^E4	VLKFHLSCI	80	88	9	HLA-A*02:03	0.6	12.38	18.41
62	HPV59	E1^E4	HTPPQRPPK	22	30	9	HLA-A*30:01	0.2	9.29	13.46
63	HPV59	E1^E4	YPLLDLLSNY	12	21	10	HLA-B*35:01	0.25	35.57	16.4
64	HPV59	E1^E4	TTVTTQSSV	66	74	9	HLA-A*68:02	0.5	13.14	31.09
65	HPV59	E1^E4	SSVCIQATTR	72	81	10	HLA-A*68:01	0.6	24.9	35.97
66	HPV59	E1^E4	SLPACQWTTV	59	68	10	HLA-A*02:03	0.7	21.77	27.62
67	HPV66	E1^E4	SVTTPTVEV	73	81	9	HLA-A*68:02	0.4	7.99	28.75
68	HPV66	E1^E4	TTPTVEVHV	75	83	9	HLA-A*68:02	0.4	5.02	22.42
69	HPV68	E1^E4	YPLLNLLPTY	12	21	10	HLA-B*35:01	0.15	12.58	24.04
70	HPV68	E1^E4	WTVSTSHSSV	64	73	10	HLA-A*68:02	0.35	16.06	17.8
71	HPV68	E1^E4	LLNLLPTYR	14	22	9	HLA-A*31:01	0.45	14.68	24.29
72	HPV68	E1^E4	STSHSSVEV	67	75	9	HLA-A*68:02	0.5	6.91	39.14
73	HPV68	E1^E4	VQAKTKDGAF	75	84	10	HLA-B*15:01	0.55	13.72	8.98
74	HPV73	E1^E4	MADSAPVKY	1	9	9	HLA-B*35:01	0.3	9.23	11.26
75	HPV73	E1^E4	GPWIVCITY	50	58	9	HLA-B*35:01	0.4	15.39	24.35
76	HPV82	E1^E4	APRHPLLQL	8	16	9	HLA-B*07:02	0.1	5.6	6.14
77	HPV82	E1^E4	VPTAPRHPL	5	13	9	HLA-B*07:02	0.2	4.78	9.86
78	HPV82	E1^E4	SPRCPWTPA	57	65	9	HLA-B*07:02	0.2	5.9	11.58
79	HPV82	E1^E4	WTPATTKYTV	62	71	10	HLA-A*68:02	0.3	8.83	24.17
80	HPV82	E1^E4	LLQLLNSYR	13	21	9	HLA-A*31:01	0.6	19.82	37.8